Energy Matters

Think of mescore as a vital sign for your mitochondria. It combines the 13 core functions measured by your mescreen™ test into one weighted score. That score is then compared with thousands of other tests in the mescreen™ database, so your result is shown as a percentile from 0 to 100.

Your score places you in one of 17 profiles, grouped into four ranges: Critical Support Needed, Functional Vulnerabilities, Adaptive Function and Elite Mitochondrial Performance. Each profile comes with its own summary and a phased action plan.

Because it's a single number, mescore makes change easy to see. Many people retest about every 12 weeks while adjusting their routine, then every 6–12 months once things are stable.

Your mitochondria turn food and oxygen into ATP, the energy every cell runs on. The Energy Profile measures how much oxygen your cells use, which gives a direct look at how hard your mitochondria are working.

• Baseline Respiration: how much energy your mitochondria make at rest. Too low points to sluggish output; too high means they're overdriven.
• Mitochondrial Efficiency: how much energy leaks away instead of becoming ATP.
• Mitochondrial Potential: the extra capacity your cells can call on under stress, like a reserve tank.

A strong Energy Profile means efficient energy with little waste and plenty in reserve, which supports endurance and recovery.

When mitochondria make energy, they also give off reactive oxygen species (ROS), a kind of cellular exhaust. A little is normal and even useful, because cells use it to send signals. Too much becomes oxidative stress, which can damage cell membranes and wear down the mitochondria themselves.

• Baseline ROS: oxidative stress at rest.
• Stressed ROS: oxidative stress when your cells are challenged.

Some people look fine at rest but release bursts of ROS under pressure, a bit like an engine that runs well until it's pushed hard and starts to overheat. Comparing the two shows how well your antioxidant defenses keep up.

Mitochondria don't work alone. Inside each cell they connect into a living network, constantly joining together (fusion) and splitting apart (fission) to share resources, repair damage and respond to demand.

In healthy cells this network is dense and well connected. Unhealthy mitochondria form sparse, fragmented networks: they break into small, isolated pieces that can't share energy or signal to each other well, so the whole system can't run efficiently.

• Baseline Mito-Network: how stable your network is at rest.
• Stressed Mito-Network: whether it holds together or starts to fragment under stress.

Results range from Strong Network to Disrupted Network.

Your cells have two ways to make energy. Mitochondria use oxygen to make ATP efficiently, getting far more energy out of every unit of fuel. Glycolysis breaks down glucose without mitochondria. It's quick and handy for short bursts, but it makes much less energy and isn't sustainable as a main source.

In a healthy balance, mitochondria do most of the steady work and glycolysis steps in for quick demands. When mitochondria struggle, cells lean harder on glycolysis, like running on a generator instead of the main power grid.

• Mitochondrial Energy: how much of your ATP comes from mitochondria.
• Glycolysis Energy: how much comes from glycolysis.

A balanced result means your body can switch between fuel sources easily, often called metabolic flexibility.

Review your results with a mescreen™ mitochondria expert. Many people retest every 3–4 months while adjusting their plan.